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Meet the Azure Cielo 3 and Cielo 6

Real-time PCR systems

The Azure Biosystems™ Cielo™ 3 and 6 real-time PCR Systems are designed to offer smart protocols, high quality data, robust durability and an intuitive user experience.

Our novel fiber optic detection system allows for enhanced sensitivity and speed. 3 or 6 standard channels let you analyze a variety of commercially available dyes, already in your workflow. Onboard software operated by a 10.2″ touchscreen minimizes footprint and saves you bench space.

Easily connect to your Cielo via Wi-Fi, ethernet, USB or LAN. Get notified after each completed run and even remotely access protocols and files.

Cielo 3 Cielo 6
SYBR™ Green, EvaGreen™, FAM™
VIC®, HEX™, JOE™, CAL Fluor® 540, CAL Fluor® Orange 560,
ROX™, TEX®615, CAL Fluor® Red 610
CY®5, Quasar®670, Liz® Mustang Purple®
CY® 5.5

Other dyes/probes are possible depending on the system configuration


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brochure-coverCielo Brochure (PDF)

brochure-coverUsing the Azure Cielo™ Real-Time PCR System for SARS-CoV-2 viral RNA detection (PDF)


Cielo 3 | Cielo 6


  • Quantitative and qualitative gene expression analysis
  • miRNA analysis
  • Genetic mapping
  • Genetic fingerprinting
  • NGS library quantification
  • 3 or 6 channel multiplex ability
  • Pathogen quantification

Key Features

  • Tested durability up to 1000 repeat experiments. 1 year standard warranty
  • Marlow Peltier heating block with 12 gradient temperature zones
  • 6.0 °C/sec ramp rate
  • 96-well format for semi-skirted or un-skirted plates
  • Fiber optic detection for 16-wells simultaneously
  • 3 or 6 optical channels for multiplexing
  • Sensitivity up to 1 copy of amplified DNA, 10 logs of dynamic range
  • Open source chemistry, including FAST. ~20 minute run-time
  • Easily export data via Wi-Fi, ethernet, USB or LAN. Get notified after each completion