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DNA

Sapphire Biomolecular Imager Used in Landmark Study of DNA Repair Pathway

The non-homologous end-joining (NHEJ) pathway is one of two pathways responsible for repairing double-stranded breaks in cellular DNA. Double-stranded breaks can be formed by ionizing radiation or mutagenic chemicals, or as intermediates during normal processes such as the recombination of DNA segments required to create antibody and T cell receptor diversity. In contrast to homologous […]

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Green tea

Sapphire Used in Study of Green Tea’s Anti-cancer Effects

Recent work published by Zhao et al in nature communications lends insight into a potential mechanism for the anti-cancer activity of green tea.   The health benefits of drinking tea, particularly green tea, has been the subject of intense investigation. A large number of epidemiologic studies have examined whether tea consumption can reduce cancer risk, with […]

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Insight into Hepatitis B virus replication gained from phosphor imaging of Southern blots with the Sapphire Imager

In a recent publication, Ji Xi et al examined the role of the linker region of the Hepatitis B virus (HBV) core protein, a protein essential for viral replication. The C-terminal domain of the core protein contains multiple phosphorylation sites that are dynamically phosphorylated and dephosphorylated by cellular kinases and phosphatases throughout the viral life […]

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Customer Interview – Using the Azure c600 to Study Innate Immunity – Thiago Soares, PhD (National Institutes of Health, Bethesda, MD)

“I instantaneously got excited about the [Azure c600]: the layout was very simple, it was compact, and had a user-friendly software– so for me, it was very convenient.”   What is your current position? I have been a Postdoctoral Fellow at the NIH/NIAD, in Bethesda, MD for the past 3.5 years. Before, I worked as […]

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