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Archive | Fluorescence imaging

Nice Western Blot

What is Western Blotting?

Your common Western blotting questions, answered Western blotting is a widely used analytical technique that can identify one or more specific proteins in a complex mixture of proteins. It is a powerful tool that provides information about the presence, size, and under the right conditions, even the amount of a protein. Though commonly used and […]

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Visualization of the Covid-19 virus

Investigating S-acylation of the SARS-Cov-2 Spike Protein Leads to New Insights into Viral Infectivity

A better understanding of coronavirus biology can enable development of new antivirals to help stop COVID-19 and prevent future pandemics. In recent work, Puthenveetil et al. characterized S-acylation of the Spike (S) protein of SARS-CoV-2. This post-translational modification is known to be important to the viral replication cycle of other viruses across multiple virus families […]

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Black tube sponges

The mechanism of action of a potential anti-cancer therapeutic: new technique to monitor subcellular environments

Callyspongiolide (CSG), derived from marine sponges, is highly toxic to human cancer cell lines from a variety of origin tissues and presents a potential cell-killing agent to be included in antibody-drug conjugates for anti-cancer therapeutics. CSG-mediated cell death doesn’t appear to occur via the canonical apoptosis pathway because cell death is not blocked by caspase […]

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TotalStainQ

Why is Total Protein Normalization Important?

If you love Western blotting as much as we do, you’ll have noticed a growing trend toward using total protein staining rather than housekeeping proteins to normalize for load. But what does total protein normalization (TPN) involve and what advantages does it offer? Read on to find out and get your hands on a free […]

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